Terence Kongolo has been ruled out for the rest of the season with a foot injury.
The news is a big blow for promotion-chasing Fulham, who signed the defender on loan from Huddersfield Town less than a month ago.
Kongolo has not started a league game for the Whites, who are third in the Championship table and in the thick of the battle for a place in the top flight.
He suffered the injury just after coming on as a substitute during Fulham’s recent win at Blackburn.
Kongolo moved to west London after falling out of favour at Huddersfield, who signed him from Monaco for £18.5m in the summer of 2018.
On a brighter note for Fulham, Anthony Knockaert could be back in the squad for Saturday’s home game against Barnsley.
Knockaert missed Wednesday’s 1-1 draw at Millwall because of illness but is expected to be available this weekend.