Kurt Zouma and John Obi Mikel both start for Chelsea at Goodison Park, with Gary Cahill and Willian dropping to the bench.
Captain John Terry returns to the line-up, replacing Cahill, having been suspended for the defeat to Crystal Palace last time out.
Mikel plays alongside Nemanja Matic in the heart of the midfield, with Cesc Fabregas pushed forward into an attacking role, flanked by Eden Hazard and Pedro.
Summer signing Asmir Begovic plays in goal following the knee injury to Thibaut Courtois.
Everton make two changes, with Brendan Galloway being passed fit to play at left-back in place of the injured Bryan Oviedo.
Muhamed Besic comes into midfield, with Tom Cleverley ruled out for up to eight weeks with the ankle ligament damage he suffered in the goalless draw with Spurs.
New signings Aaron Lennon and Ramiro Funes Mori are both among the Everton substitutes, as is veteran midfielder Leon Osman.
Subs: Robles, Mirallas, Lennon, Naismith, Deulofeu, Osman, Funes Mori.
Chelsea: Begovic; Ivanovic, Zouma, Terry, Azpilicueta; Mikel, Matic; Pedro, Fabregas, Hazard; Costa.
Subs: Blackman, Cahill, Loftus-Cheek, Kenedy, Willian, Falcao, Remy.