Referee: Bobby Madley (Wakefield, Yorkshire)
Five key battles: click here
Match in a nutshell: Chelsea need a victory against the Saints to kick-start their season after a poor start.
Injuries and suspensions
Ruled out: Thibaut Courtois (knee).
Fitness tests: None.
Unavailable: Diego Costa (game two of three-match ban).
Ruled out: Fraser Forster (knee), Florin Gardos (knee).
Fitness tests: Jordy Clasie (ankle ligament).
Subs from: Blackman, Terry, Baba, Djilobodji, Aina, Mikel, Loftus-Cheek, Ramires, Oscar, Traore, Kenedy, Remy.
Southampton: Stekelenburg; Soares, Fonte, Van Dijk, Bertrand; Wanyama, S. Davis; Mane, Ward-Prowse, Tadic; Pelle.
Subs from: K. Davis, Gazzaniga, Martina, Yoshida, Caulker, Targett, Romeu, Juanmi, Reed, Ramirez, Long, Rodriguez.
Form guide – last five league matches
Chelsea total: D W L L W (7 points)
Home: W L D W D (8 points)
Southampton total: W L D W D (8 points)
Away: D D D L L (3 points)
Top scorers – all competitions
Chelsea: Willian 3; Costa 2, Oscar 2, Pedro 2, Ramires 2; Azpilicueta 1, Fabregas 1, Falcao 1, Hazard 1, Kenedy 1, Matic 1, Zouma 1.
Southampton: Pelle 6; Long 4, Mane 4, Tadic 4; Rodriguez 3; Van Dijk 1.
Last five meetings
15 March 2015: Chelsea 1 Southampton 1
28 December 2014: Southampton 1 Chelsea 1
1 January 2014: Southampton 0 Chelsea 3
1 December 2013: Chelsea 3 Southampton 1
30 March 2013: Southampton 2 Chelsea 1
Chelsea 2 wins, Southampton 1 win, 2 draws