Jordan Cousins and Pawel Wszolek are leaving QPR after being told the club will not be taking up options to extend their contracts.
Rangers also have options to extend the contracts of Jake Bidwell and Joel Lynch, whose current deals are about to expire too. Confirmed decisions on their futures are imminent.
Alex Baptiste is also out of contract, as is Angel Rangel, who joined the club on a short-term deal last August before being retained for the rest of the season.
Defenders Bidwell and Lynch and midfielder Cousins were signed in the summer of 2016 from Brentford, Huddersfield and Charlton respectively.
Polish winger Wszolek was brought in on loan from Italian side Hellas Verona that summer and signed on a permanent deal the following January.