Gary Cahill has been left out of the Chelsea starting line-up for the game at Goodison Park, where the Blues will again play without an out-and-out striker.
With Alvaro Morata suspended, Eden Hazard is set to lead the Chelsea attack, supported by Pedro and Willian.
Cahill is a substitute, with Antonio Rudiger starting and Cesar Azpilicueta captaining the side. Marcos Alonso is back after suspension.
Cesc Fabregas is also on the bench, with Tiemoue Bakayoko again starting alongside N’Golo Kante in midfield.
Teenage striker Callum Hudson-Odoi is again among the substitutes.
Meanwhile, Wayne Rooney has been left out of Everton’s matchday squad, while defender Michael Keane returns.
Yannick Bolasie is back in the Everton squad after more than a year out. The winger is on the home side’s bench.
Everton: Pickford, Keane, Jagielka, Kenny, Martina, Schneiderlin, Lennon, Gueye, Davies, Sigurdsson, Calvert-Lewin
Subs: Robles, Williams, Bolasie, Ramirez, Niasse, Holgate, Baningime.
Chelsea: Courtois; Azpilicueta, Christensen, Rudiger; Moses, Kante, Bakayoko, Alonso; Willian, Hazard, Pedro.
Subs: Caballero, Fabregas, Drinkwater, Zappacosta, Batshuayi, Cahill, Hudson-Odoi.